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Zbog sličnosti oksidativnih procesa, diazepam kompetitivno inhibira metabolizam ketamina. Premedikacija sa diazepamom dovodi do produženog poluvremena eliminacije ketamina, što za rezultat ima njegovo pojačano dejstvo. Pojačana sedacija.S obzirom na to da je rizik od pojave fenomena obustave/rebound fenomena veći ukoliko se terapija naglo pre
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